The nursing profession has long cared for and sought to heal the sick. The nurse today functions within healthcare teams inside hospital systems or in outpatient settings. Throughout the nursing profession, ethics has been important. The Nightingale Pledge was the ethical standard for the ideal nurse adapted from the Hippocratic Oath and named after Florence Nightingale. It held the nurse responsible to God, forbid harming the patient, and commissioned nurses to promote the health of patients and assist physicians in this endeavor. The profession advanced in 1965 to create nurse practitioners to address the needs of access to healthcare. Nurse practitioners are nurses with advanced graduate-level training to examine, diagnose, treat, and prescribe in order to help and heal patients. The nurse practitioner role was originally created for nurses to assist physicians to see more patients independently. Unfortunately, nurse practitioners do not have any ethical framework or oath that shapes their practice. Only one proposal of a nurse practitioner code of ethics has been attempted. There are no oaths for nurse practitioners to serve as an ethical framework for nurse practitioners. Like the Nightingale Pledge that was fashioned from the Hippocratic Oath, nurse practitioners ought to practice from the moral framework of Hippocratism. Moreover, medicine and nursing were both influenced greatly by early Christianity, and Christian nurse practitioners ought to practice Christian Hippocratism. In order to base the virtuous nurse practitioner’s practice in an ethical framework, an Oath for Nurse Practitioners is proposed.